Antonio Conte stayed on course for a domestic double in his first season in England as Chelsea beat 10-man Manchester United 1-0 in their FA Cup quarter-final at Stamford Bridge.
Kante’s second Chelsea goal six minutes into the second half secured a quarter-final win for the Premier League leaders, who won for a club record 13th successive home game.
Hopes of a double in Conte’s first season in charge remain alive.
Both Kante’s Chelsea goals have come against United, who have not beaten the Blues in 12 attempts, since October 2012.
Mourinho, whose side won the EFL Cup last month, had never lost a FA Cup quarter-final. He has now.
David de Gea made fine saves in quick succession to deny Eden Hazard and Gary Cahill and a smash and grab raid for United appeared possible.
But Herrera was dismissed for two fouls on Eden Hazard following what looked like an edict to target the Belgium playmaker.
United players surrounded referee Michael Oliver to complain, but captain Chris Smalling had been warned seconds earlier about repeated fouls on Hazard after one by Phil Jones.
The managers were kept apart moments later after Marcos Alonso tumbled to the floor after being brought down.
The visitors attempted to intimidate and impose themselves, but Chelsea – and Kante and Hazard in particular – were indomitable.
Marcus Rashford, who came off his sick bed to play – with Zlatan Ibrahimovic suspended, and Wayne Rooney and Anthony Martial injured, created United’s best chance for himself but Chelsea keeper Thibaut Courtois saved with his feet to set up a semi-final against Tottenham at Wembley.
The last time Mourinho was an FA Cup manager on this ground, Chelsea conceded a two-goal lead to lose to League One Bradford.
And he suffered his biggest defeat in English football when Chelsea won 4-0 in the Premier League last October.
Mourinho rebuked Conte on that occasion after the Italian had implored the crowd to cheer with Chelsea coasting.
Conte vowed not to tone down his exuberance in his technical area and he refused to be cowed as Mourinho’s men made their presence felt.
Marcos Rojo’s challenge from behind on Diego Costa set the tone as United repeatedly resorted to the cynical, while Jones was deployed as Hazard’s shadow.
- Chelsea are now unbeaten in 12 games against Man Utd in all competitions (W7 D5) since a 2-3 home defeat in October 2012.
- Indeed, only twice in their history have Manchester United had a longer winless run against a certain opponent (13 vs Liverpool in 1927 and 13 against Leeds in 1972).
- The Blues’ victory means there will be three London teams in the FA Cup semi-finals for the first time since 2002 (Arsenal, Chelsea and Tottenham).
- Jose Mourinho’s side received their third red card of the season, with two of those being shown to Ander Herrera.
- All three of N’Golo Kante’s goals in English football have been scored at home, with two of them coming in games against Manchester United this season.
- Man Utd had just 28% possession against Chelsea, their lowest figure in a single match this season.
- Chelsea have reached their 22ndFA Cup semi-final, the fifth highest total in the competitions history (Arsenal 29, Man Utd 28, Everton 26, Liverpool 24).